Thanks for reaching out with your question.
The Bose 161 speakers are designed to be connected directly to an receiver or amplifier, these cannot be directly plugged into your MAC computer. If you wish to have this work with your computer, you will have to have your computer wired to an amplifier then continue to have your 161 speakers connected to this also to complete the chain.
I hope this helps, do let us know if you have any further questions.
Nov 12, 2015