Whole-home Audio

[bcut1150]

I am interested in installing a stereo system that I can have throughout my whole house. Approximately 2,000 SQ-FT living space. I am looking for recommendations for what I should get to create this system. Which amplifier? how many speakers per room or per SQ-FT? what should I consider if I want to be able to isolate certain areas? basically can anyone give me a breakdown of what I need to get and need to do to have a well appointed home audio system?